NFL Pick: Cardinals at 49ers

Arizona Cardinals (-3.5) at San Francisco 49ers

I doubt CBS/NFL Network is pleased with this matchup. Cardinals QB Carson Palmer is in concussion protocol and will not play, so Drew Stanton will start for Arizona. Stanton came on in relief of Palmer last week against the Rams, and he promptly threw 2 INTs, although one was on a Hail Mary at the end of the game. The Cardinals will be getting RB David Johnson involved early and often. The San Francisco run defense is really hurting right now after unfortunately losing Navorro Bowman for the season. Some of the 49er cornerbacks are playing pretty well, and they will be hoping that its pass rush will be getting some of a boost with the return of Aaron Lynch, who is returning from a 4 game suspension. I am reading his snaps will be limited, but I’m sure he’ll be in on passing downs.

San Francisco will also be looking to establish the run, as Arizona has a very strong pass rush (11 sacks) and some very good corners. They won’t have to worry about the deep ball, because 49ers QB Blaine Gabbert does not have the confidence to make those throws. Yep, nothing else interesting here.

I’ve been clueless on Thursday night games this year, and that continues with this game. I know the 49ers won’t be able to move the ball too well, but I don’t think Arizona will either. I have to believe Arizona wants and needs this game more, so I’m making my pick based on that. The 49ers really didn’t look good in the second half against Dallas last week, anyway.

Pick: Cardinals 17 49ers 10

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